How many of us are old enough that a Labradoodle wasn’t labeled as such when we first started practice? The labradoodle was officially “started” in 1989 as a breed intended to have low shedding potential. They have gained in popularity over the years and are now extremely popular as a breed worldwide. They are not a recognized breed by the AKC as of 2024, but that hasn’t stopped many breeders from providing pedigrees. Although typically considered a mix of just a labrador and a poodle, they can also be mixed with Irish Water Spaniels, Curly Coated Retrievers and even Cocker Spaniels. One of the proclaimed benefits of a mixed breed dog is the perceived lower risk of health problems. Several studies have refuted this and certainly we see a similar incidence of seizures in Labradoodle dogs compared to Labrador dogs. Idiopathic epilepsy has a known genetic inheritance in the Labrador, and it is suspected in the Poodle. A recent study evaluated Labradoodle dogs with idiopathic epilepsy, presumptive epilepsy and those with epilepsy of unknown origin. They included 40 dogs in the study. Males were over represented in this study (supported in other studies) and most of the dogs were neutered before their first seizure.
Generalized seizures were noted in 25 of 40 dogs, 12 of 40 had focal and generalized seizures and three displayed only focal seizures. The average age of onset was 2.3 years +/- 1.3 years which is similar to the Labrador. Note that the study limited age as an inclusion factor so this could be slightly skewed. The average number of seizures per year in this cohort was 5.4 seizures +/- 6.5 seizures, also similar to the Labrador. Poodles tend to have fewer, less frequent seizures and rare status or clusters. There were similar numbers of seizures in the treated, and non-treated groups, but remember that we treat frequent seizures, and don’t tend to treat infrequent seizures! Seizures were scored for severity on a 1-10 scale (1: not severe, 10 – very severe) and, although a subjective measure, was considered 6.9 on average +/- 2.0. About 33% of the dogs had cluster seizures (more than 1 seizure/24 hours) and the other remaining dogs had occasional clusters or no clusters.
This study utilized a questionnaire to determine the personality of the dog, and home setting. Eleven dogs were described as nervous/anxious dogs and the remainder were described as vivid, cheerful and stable. Although more seizures/year were noted in the anxious group, this was not statistically significant. No correlation was noted between tick/flea/food and vaccinations in this group of dogs. However, all owners thought that they identified precipitating factors that were all considered ‘stressors.’ Some examples provided included visits to the groomer, vet visits, home visitors and sounds. Both the ictal and post ictal phase were considered stressful for some of the owners, however more owners referred to the ictal phase as the most stressful part of the event. Owners scored their own and their pet’s QoL as fair to good for most of the study. However financial cost was considered a moderate problem (an average of 5.1 on a 10 point scale) for owners.
What should we take away from this article? An awareness of the prevalence of idiopathic epilepsy in Labradoodles should be an important take away from this article. Secondly, it is helpful to note that generalized seizures are common, however focal seizures are also reported in Labradoodles. If you have a desire to read the remainder of the article it can be found here: https://doi.org/10.3389/fvets.2024.1459260
Thanks for reading! I hope you have a good week and stay warm!