sleep

Sleep and Neuropathic Pain in Cavalier King Charles Spaniels

A study was presented at ACVIM this year (2025) by Drs. Parker et al that evaluated sleep scores, neuropathic pain scores and perceived QOL by owners in a cohort of Cavalier King Charles Spaniels. The premise for this study was that poor sleep might exacerbate chronic pain in humans. They enrolled 68 CKCS, 37 of whom were diagnosed with caudal occipital malformation syndrome (COMs). Of these 37 dogs, 19 of them were considered to be clinical for the diagnosis and 18 were not clinically affected. Interestingly, dogs with clinical COMS also had greater difficulty falling asleep, ability to stay asleep for long periods of time, and overall poorer sleep quality. It was noted that more dogs slept with their heads propped up than not in the clinically affected group.

Why are they sleeping more poorly?

The authors propose that dogs with COMs may have chronic pain, which results in greater sleep disturbances. Additionally, part of the COMs complex is kinking of the brainstem which is where respiratory centers and the reticular activating system (RAS) are housed. The authors proposed that disrupted sleep could be due to alterations of these systems as well. Lastly, these dogs are brachycephalic which can result in snoring while sleeping, which is also linked to poorer sleep scores.

What do we do about it?

Owners can purchase a “fit bark” or other activity monitor that tracks their dog’s sleeping patterns. If frequent sleep disturbances are noted, initiation of pain management, investigation into brachycephalic airway surgery, or allowing for a “propped” head position might be indicated to improve sleep. The pain management medication I suggest in these cases is gabapentin or pregabalin, however excessive sedation should be monitored.

Although not exactly in line with our summer of cranial nerves, I thought this study was interesting and worth sharing. Stay tuned for more Tidbits gleaned from the national meeting this year!

Thanks for reading. I hope you have a wonderful week and enjoy these dog days of summer with those you love.

How is Sleep Linked to Seizures?

I had the privilege to be involved in a prospective study regarding the effects of sleep and epilepsy. This study was published this week in the Journal of Veterinary Internal Medicine (see below for a link).

Disrupted sleep is common in human patients with epilepsy. Is the same true for dogs with epilepsy?

Dr. Starr Cameron spearheaded a study at the University of Wisconsin-Madison, and enrolled dogs with confirmed or suspected epilepsy, fit them with a FitBark(TM) the dog equivalent of a FitBit(TM) and watched their sleep patterns over 12 weeks. This study was one part of a multi-part study using the FitBark(TM) technology.

So, what is the answer?

Interestingly, a statistically significant change in sleep patterns was NOT noted. These were age and breed matched dogs, too. There was a trend toward poorer sleep for dogs receiving higher doses of bromide, but it was not noted at lower doses.

What is the relationship with sleep and seizures?

In human epileptic patients, seizures beget poor sleep and poor sleep can result in an increased frequency of seizures. This wasn't shown in our dog population, but that doesn't mean that it isn't a concern for some dogs. What do we take away from this? Keep an eye on the sleep pattern of your epileptic patients and consider sleep aids if they are restless. Oh, and stay tuned for more results looking at sleep and seizures in dogs - this is a hot area of research right now. :)
Article: https://onlinelibrary.wiley.com/share/JD24HPYCTIRKYTBVSJZA?target=10.1111/jvim.16205

I hope you have a great week! Let me know if you have an epileptic patient that needs a little extra assistance - I'd love to help!